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霍长虹博士-教授

发布时间:2020-11-10   浏览次数:0



霍长虹,博士,教授,博士生导师,太阳成集团tyc33455cc天然药物化学教研室主任。2005年毕业于北京大学获生药学博士学位。为省级线下一流课程《天然药物化学》的课程建设负责人,荣获河北省省级教学成果二等奖1项,为多篇河北省优秀硕士论文指导教师。

主要研究方向

天然药物化学成分与活性筛选,已主持完成国家自然科学基金面上项目、中国博士后科学基金项目、河北省自然科学基金项目、河北省教育厅重点项目。为第十届中国药学会施维雅青年药物化学奖获得者,荣获河北省自然科学二等奖1项,河北省中医药学会科学技术一等奖2项。为多种国际期刊同行评议人。

作为第一作者或通讯作者发表的SCI论文

1.Naphthacemycins from a Streptomyces sp. as protein-tyrosine phosphatase inhibitors. Journal of Natural Products, 2020, 83(5): 1394-1399.

2.Azaphilones with protein tyrosine phosphatase inhibitory activity isolated from the fungus Aspergillus deflectus. Phytochemistry, 2020, 170: 112224.

3.A new tetracyclic triterpenoid from the fresh bark of Ailanthus altissima. Chemistry of Natural Compounds, 2020, 56(3):477-480.

4.Phenolic components of the aerial parts of Achillea alpina. Chemistry of Natural Compounds, 2019, 55(2):337-339.

5.A New Bisepoxylignan Glucoside from the Leaves of Forsythia suspensa. Chemistry of Natural Compounds, 2018, 54(6):1038-1040.  

6.A chemometric-assisted LC-MS/MS method for the simultaneous determination of 17 limonoids from different parts of Xylocarpus granatum fruit. Analytical and Bioanalytical Chemistry, 2017, 409:4669-4679.

7.Study on the metabolites of isoalantolactone in vivo and in vitro by ultra performance liquid chromatography combined with Triple TOF massspectrometry. Food Chemistry, 2017, 214(1):328-338.

8.Identification of in vitro and in vivo metabolites of alantolactone by UPLC-TOF-MS/MS. Journal of Chromatography B, 2016, 1033:250-260.  

9.Polyhydroxytriterpenoids and Phenolic Constituents from Forsythia suspensa (Thunb.) Vahl Leaves. Journal of Agricultural and Food Chemistry, 2016, 64(1):125-131.

10.Triterpenoids and Steroids from the Leaves of Forsythia suspensa. Chemistry of Natural Compounds, 2015, 51(1):178-180.  

11.Two New Non-Taxoids from Leaves of Taxus cuspidate. Chemistry of Natural Compounds, 2014, 50(4):603-605.

12.A New Taraxastane-Type Triterpene from the Flowers of Inula cappa. Chemistry of Natural Compounds, 2014, 50(5):850-852.

13.Chemical Composition of Achillea alpina. Chemistry of Natural Compounds, 2014, 50(3):534-536.

14.A New Limonoid from Xylocarpus granatum. Chemistry of Natural Compounds, 2014, 50(2): 314-316.

15.A new glyceride from the seeds of Xylocarpus granatum. Chemistry of Natural Compounds, 2013, 48(6): 934-937.

16.Cytotoxic flavonoids from the flowers of Achillea millefolium. Chemistry of Natural Compounds, 2013, 48(6): 958-962.

17.Chemical Constituents of Plants from the Genus Forsythia. Mini Reviews in Organic Chemistry, 2012, 9(3):303-318.

18.Xylocarponoids A and B, Unique 28C skeleton limonoids from Xylocarpus granatum. Tetrahedron Letters, 2010, 51(4):754-757.

19.New neolignan glycosides and a new cerebroside from Symplocos caudata. Chemistry of Natural Compounds, 2010, 46(3):343-347.

20.Two new eudesmanes from Inula helenium. Chemistry of Natural Compounds, 2010, 46(3):373-376.

21.Chemical Constituents of Plants from the Genus Melia. Chemistry & Biodiversity, 2010, 7(4):839-859.

22.Protolimonoids from the seeds of Xylocarpus granatum. Biochemical Systematics and Ecology, 2009, 37(3):218-220.

23.Xylomexicanins A and B, New Δ14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum. Zeitschrift fuer Naturforschung, C, 2009, 64c (1/2):37-42.

24.Chemical Constituents of plants from the Genus Xylocarpus. Chemistry & Biodiversity, 2009, 6(9):1293-1308.

25.Neolignan glycosides from Symplocos caudata. Phytochemistry, 2008, 69(3):788-795.

26.A new 5,11- Epoxymegastigmane Glucoside from Acanthus ilicifolius. Natural Product Research, 2008, 22(10):896-900.

27.Chemical Constituents of Plants from the Genus Excoecaria. Chemistry & Biodiversity, 2008, 5(11):2356-2371.

28.Canataxpropellane, a novel taxane with a unique polycyclic carbon skeleton (tricyclotaxane) from the needles of Taxus canadensis. Tetrahedron Letters, 2007, 48(15):2721-2724.

29.Structural determination of a new 2(320) abeotaxane with an unusual 13-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata. Magnetic Resonance in Chemistry, 2007, 45(4):527-530.

30.Two new taxanes from Taxus canadensis. Biochemical Systematics and Ecology, 2007, 35(12):909-913.

31.A new taxol analogue from the leaves of Taxus cuspidata. Biochemical Systematics and Ecology, 2007, 35(10): 704-708.

32.A New Metabolite with A New Substituted Pattern from the Seeds of the Chinese Yew, Taxus mairei. Chemistry & Biodiversity, 2007, 4(1):84-88.

33.Chemical Constituents of Plants from the Genus Symplocos. Chemistry & Biodiversity, 2007, 4(1):1-11.

34.Chemical Constituents of plants from the Genus Cerbera. Chemistry & Biodiversity, 2007, 4(7):1438-1449.

35.Structure elucidation and complete NMR spectral assignments of a new benzoxazolinone glucoside from Acanthus ilicifolius. Magnetic Resonance in Chemistry. 2005, 43(4):343-345.

36.Benzoxazinones from Acanthus ilicifolius. Biochemical Systematics and Ecology. 2005, 33(6):643-645.